IF YOU ARE MISSING MSVCR100.DLL INSTALL THE MS VC++ REDISTRIBUTABLE HERE: http://www.microsoft.com/en-us/download/details.aspx?id=26999
Now that's out of the way - for the people with error in Pythons multiprocessing libraries (the one that ends with "TypeError: WriteFile() argument 1 must be integer, not None"): thanks for the system specs. One thing I notices is that you're running Core i7s which have 8 threads, which leads me to think that RPGMaker Trans is going too parallel for Windows to handle. Hence the next version of RPGMaker Trans will have a limit on the number of processes it uses, and hopefully that will be a cure.
As to me testing this out: I don't have a Windows machine with an 8 thread processor in, so that could be tricky. I'll see if I can set something up, but there's a very high chance that'll I'll be working blind on this one.
EDIT2: And it wasn't that... it seems to be a more fundamental bug in Python, but it's fixed anyway.